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Without some chemicals (like oxygen), life as we know it would not be possible

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Big Tobacco in the Big Apple How New York City Became the Heart of the Tobacco Industry and Anti Smoking Activism The American Tobacco Company Reach for a Lucky Instead of a Sweet (1:15) Catalogue of Presents for Tobacco Tags and Coupons The American Tobacco Company 1916 The famous original cigarette: Ask Dad, he Knows Advertisement for the American Tobacco Companys Sweet Caporal cigarettes 1916 keeps your throat cool all day long Advertisement for the American Tobacco Companys Sovereign cigarettes 1916 Perfect Satisfaction Advertisement for the American Tobacco Companys Mecca cigarettes 1916 11,105* doctors say Lucky Strikes prevent throat irritation Advertisement by the American Tobacco Company The Literary Digest November 12, 1927 20,679* Physicians say Luckies are less irritating' Advertisement by the American Tobacco Company Liberty Magazine July 5, 1930 To keep a slender figure, No one can deny, Reach for Lucky instead of a sweet Advertisement by the American Tobacco Company TIME Magazine 1929 Physicians and Physiques Lucky Strikes Do you think from your experience with Lucky Strike cigarettes that they are less irritating to sensitive or tender throats than other cigarettes, whatever the reason? This question posed to physicians became the basis for Lucky Strikes claim that Luckies are less irritating and provided protection for the throats of smokers

The mechanism appears to be that smoking induces inflammatory mediators and promotes keratinocyte proliferation